András Málnási-Csizmadia’s lab

February 13, 2012: Our new research article appeared in Nature Structural and Molecular Biology

Balazs Jelinek — Fri, 17 Feb 2012 15:23:18 +0000

Our new paper “A novel actin binding site of myosin required for effective muscle contraction” just appeared in NSMB. The paper deals with the conserved actin-binding region of myosin named the ‘activation loop’. It interacts with actin, accelerateing the movement of the relay, stimulating myosin’s ATPase activity. This interaction results in efficient force generation, but it is not essential for the unloaded motility, as we demonstrated in vivo using transgenic Caenorhabditis elegans strains.

February 7, 2012: Open position

Balazs Jelinek — Tue, 07 Feb 2012 13:47:29 +0000

Postdoctoral position in molecular biology!

Application deadline: closed

January 23, 2012: Our latest research article is the cover story of JCIM

Balazs Jelinek — Thu, 02 Feb 2012 16:48:26 +0000

Our new paper “Drug Effect Prediction by Polypharmacology-Based Interaction Profiling” just appeared in the Journal of Chemical Information and Modeling (JCIM) was selected as cover story. The paper deals with our new Pattern-based Drug Design approach, and its apparition is an important milestone for us. JCIM is the second most highly cited journal of the field, and as this issue is a sample issue of JCIM the full text paper is available free of charge.

January 1, 2012: HAS Research Group started

Balazs Jelinek — Thu, 02 Feb 2012 16:13:58 +0000

The HAS-ELTE Molecular Biophysics Research Group is established, see the members here. The group is funded by the grant of the Hungarian Academy of Sciences for five years, and its project will focus on predicting relations of protein structural dynamics and enzymatic functions.

December 16-17, 2011: Rereat meeting in Visegrád

Balazs Jelinek — Thu, 02 Feb 2012 16:11:17 +0000

The Retreat Meeting with international participants, see the Programme here.

August 1, 2011: Research Communication appeared in FASEB Journal

Balazs Jelinek — Fri, 07 Oct 2011 13:39:12 +0000

FASEB Journal published in print the manuscript entitled “Temperature dependence of internal friction in enzyme reactions”, dealing with the elucidation the physical background of internal friction of enzyme reactions by investigating the temperature dependence of internal viscosity.

July 26, 2011: HAS Research Group application selected for funding

Balazs Jelinek — Fri, 07 Oct 2011 13:02:54 +0000

A new research group with András as the scientific leader will be started next January at Eotvos Lorand University. The group is funded by the grant of the Hungarian Academy of Sciences for five years, and its project will focus on predicting relations of protein structural dynamics and enzymatic functions.

July 1-2, 2011: TÁMOP conference in Dobogókő

Balazs Jelinek — Thu, 19 May 2011 11:34:11 +0000

The subproject named “Large systems in science and their computational simulation” is part of the TÁMOP project of our university (see the homepage of the project in Hungarian here). The first conference of the subproject will take place in Walden Hotel, Dobogókő, with plenary and section lectures from the 17 research groups involved. Our research group will present the news in the MIF project, and we are also organizers of this event since András is the executive leader of the subproject. A detailed description and programme of the conference can be found here.

June 1, 2011: New malnalab logo

Gabor Meszoly — Fri, 08 Apr 2011 11:43:47 +0000

Malnalab has a new logo. As the previous one, the new logo is based on an artwork of Krisztina Lehoczky, and was designed by Zoltan Simon as an illustration for the review “Emerging complex pathways of the actomyosin powerstroke“. The illustration was selected for the cover of the TiBS issue in which this review appeared end of last year.